Global Oncology-Implementing Science

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ASCO- GOIS International Webinars (GOIS-ASCO IW) Series:

Be game changers in global oncology

3^rd ASCO- GOIS International Webinars (ASCO-GOIS IW)

Topic: An overview on scientific resource-saving and better value cancer treatment approaches.

January 21, 2025 at 3.00pm-5.00pm GMT

To register: Click or browse www.icedoc.website then register (It is free)

For e-brochure: https://icedoc.website/cms/mod/forum/discuss.php?d=26

· President: Introductory note by Prof. Robin Zon, President, ASCO 2024-2025

ASCO: American Society of Clinical Oncology

GOIS: Global Oncology-Implementing Science Program , Global Oncology University ( GO-U) , www.icedoc.website . GOIS is the 1^st world professional program focused exclusively on presentation and stimulation of how via scientific exploration , to increase affordability of cancer care in the real world. (It is Free and accessible to all).

SEMCO is The South and East Mediterranean College of Oncology

The ASCO- GOIS International webinars (ASCO- GOIS IW): This series will continue the brainstorming reviewing and the discussion started in the Global Oncology-Implementing Science (GOIS) program virtual program entitled: “Be game changers in Global Oncology”

The ASCO- GOIS IW series are proposed, designed and facilitated by Prof. Ahmed Elzawawy, after discussions and approval of the leaders of the win-win scientific initiative and GOIS.GO-U. Contact: feedback@icedoc.website & worldccoperation@gmail.com

For colleagues who like to obtain certificate of different levels of “ A game changer in global Oncology” , GOIS, GO-U, At the end of series , We'll send guides for evaluation and we encourage colleagues for obtaining certificates on the program

(https://www.icedoc.website & https://icedoc.website/GOIS_Program_2023-2024.pdf

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3^rd Webinar , Title : An overview on scientific resource-saving and better value cancer treatment approaches.

Session Date / Time: January 21, 2025 at 3.00pm-5.00pm GMT

Session will be virtual and will last for 2 hours.

Goals for the (ASCO - GOIS IW) Series

· Explore the scientific and patient centered approaches to finding and validating accessible and affordable therapies for cancer care, such as real-world data, AI, preclinical models and clinical trials

· Discuss the overall impact of readily available and affordable cancer therapies for patient globally in affluent and less affluent Countries (LMICs)

Specific Goals for the 3^rd webinar:

· Give concrete overview on scientific resource-saving and better value cancer treatment approaches.

· Propose future directions for collaborative global cancer care studies and implementation.

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Ø President of the series and introductory notes for the whole series : Prof. Robin Zon, ASCO president , 2024- 2025.

https://youtu.be/0eUPIWvnejg?si=WU09k4RG0Mly3GFo

Ø Chair of the series: Prof. David Kerr , Oxford University, UK , Past Chair of ASCO International Affairs Committee. Past President of ESMO, Leader of the win-win initiative and Co-founder of GO-U & GOIS https://youtu.be/PbORxWpnLXA

Ø Co-Chair of the series: Prof. Eduardo Cazap, Argentina, MD, PhD, FASCO, President & Founder of SLACOM , Co-chair RINC , Global Oncology Patron – Ecancer , Past President UICC, Past Chair, ASCO International Affairs Committee , Leader of the win-win initiative and Co-founder of GOIS-GO-U

Ø Director: The series is designed and facilitated by: Prof. Ahmed Elzawawy

List of Panelists and faculty in Alphabetical order:

· Dr. Jacques Bezuidenhout , Belgium and South Africa . A Clinical Oncologist , and post graduates certificate on health economics, A Faculty win-win initiative and GOIS.

· Prof. Eduardo Cazap, SLACOM , RINC , ecancer , Argentina, leader , Win-win initiative & co founder GO-U & GOIS , Past President UICC, Past Chair, ASCO International Affairs Committee

· Prof Ahmed Elzawawy; Chair , Board of Directors, GO-U & Chair .The win-win Scientific Initiative, SEMCO and Past President , AORTIC & Prof. Clinical Oncology, Egypt (The Facilitator and the contact person)

· Dr. Bishal Gyawali, MD, PhD is an associate professor in medical oncology and public health sciences and scientist in Queen’s University, Kingston, Canada. Co-founder CSO.

· Pro. David Kerr, CBE MD DSc FRCP FRCGP FACP FESMO FMedSci, Past Chair, ASCO International Affairs Committee, American Society of Clinical Oncology & Oxford University, UK , Leader , Win-Win initiative, Co-founder, GOIS, GO-U

· Prof. Hussein Khaled. Prof. Medical Oncology, Ex. Minister of High Education, SEMCO , NCI, Cairo, Egypt

· Prof. Aparna R. Parikh, MD, FASCO, USA. Associate Professor of Medicine, Harvard Medical School , Director of the MGH Cancer Center's Global Cancer Care Program

· Dr. Abba Mallum, Associate Prof Radiation Oncology and Medical cancer Consultant, South Africa and active Faculty, win-win initiative and GOIS, GO-U & Rapporteur of the 3^rd ASCO-GOIS International Webinar

Prof, Twalib Ngoma, Tanzania , board of leaders , Win-win initiative, & Co-founder, GOIS, GO-U , Past President , AORTIC
Prof. Wil Ngwa, John Hopkins University, USA, Director, GHC, GO-U, board of leaders, Win-win initiative, Co-founder GOIS

· Prof. Karol Sikora, Buckingham University, UK & , leader , win-win initiative & Co-founder, GOIS, GO-U

· Prof. Enrique Soto ( Prof. Enerique Soto Perez De Celis), The Editor in Chief of ecancer, Professor of Medical Oncology & Geriatric Oncology and Associate Director for global oncology, University of Colorado , USA,

· Dr Susannah Stanway, is an honorary consultant medical oncologist at the Royal Marsden Hospital in the UK, specializing in breast cancer with an interest in global cancer care. She is a past president of the Oncology Section at the Royal Society of Medicine and she is one of the founders of London Global cancer week.

Ø Prof. Robin Zon, ASCO, President 2024-2025

Ø Rapporteur : Dr. Abba Mallum.

Materials:

Ø For all colleagues: Before the webinar, it will be enjoyable to have a read and to watch the materials that are considered the starting points of free panel and discussion of the upcoming webinar before the 3rd ASCO-GOIS webinar of January 21, 2025

1- PDF of slides 3rd ASCO-GOIS.Overview- slides-full text https://icedoc.website/3rd-ASCO-GOIS.pptx

2- Isn’t the time to change? (Communication in ASCO My connection)

https://icedoc.website/IsntTheTime.pdf

In all GOIS events and program www.icedoc.website : The objective is not to agree or not on any of the raised stimulating or brain storming points in the videos or GOIS program. What is important is to arrive-freely- together to conclusive points on: What to do and future directions to increase affordability of better value cancer via scientific approaches.

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Duration of each virtual session, 2 hours: ( RECORDED)

5 minutes: Welcome. Prof. David Kerr and Prof. Ahmed Elzawawy

5 minutes: Introductory note: By Prof. Robin Zon , ASCO, President 2024-2025

20 minutes: Overview on the topic and raised brainstorming points. ( Ahmed Elzawawy)

10 minutes. Prof. Enerique Soto: The role of ecancer in dissemination of Global Oncology and implementation science”

45 minutes: Input of panelists on the raised point and comments (s) (5 minutes for each panelist)

10 Minutes: Discussion (coordinated and facilitated)

10 minutes: Q&A

10 minutes: Conclusion and future directions ( Prof. David Kerr)

5 minutes, closing remarks. Prof. Eduardo Cazap and Prof. Ahmed Elzawawy

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The live discussion during the webinars and later feedback e-mails are welcomed for all. worldcooperation@gmail.com & feedback@icedoc.website

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Expected Attendees:

· Unlike hundreds of classical webinars, that may haven’t lasting effects , we don’t count on the number of live attendees , but on watching the recorded sessions via many tracks and webs. Then, we consider free feedback and outcome that may lasts and be a stimulation for the better by many in the real world ( for feedback http://icedoc.org/feedback.html )

Ø We'll send soon guides for evaluation and obtaining certificates on the program for colleagues who like to obtain certificate of different levels of “A game changer in global Oncology”. The Certificate will be after the end of each series. If you miss up to 50% of the live course for any problem of connection, wherever you are in the world , then don’t worry , all the recorded webinars will be available for all.

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Short information about the speakers:

President: Prof. Robin Zon, ASCO President, 2024-2025

Prof. Robin Zon, MD, FASCO, FACP, USA. President of ASCO term 2024-25 . Dr. Zon currently practices as Physician Emeritus at Michiana Hematology Oncology in Mishawaka, IN, where she previously served as President. She formerly served as Medical Director of Oncology Research at Memorial Hospital and National Cancer Institute Community Clinical Oncology Program Associate and then Principal investigator.

Chair of the series

Professor David Kerr CBE MD PhD DSc FRCP FRCGP FACP FESMO FMedSci , UK : David contributes to Oxford as Professor of Cancer Medicine, where he has worked with colleagues to build a new Institute for Cancer Medicine and Cancer Hospital. Co-Leader, The win-win initiative and Co-Director, Global Oncology-Implementing Science Courses and program, Co-founder, GO-U

Distinguished Scientific Experts -Panelists :

Prof. Eduardo L. Cazap MD, PhD, FASCO, Argentina , President & Founder -Latin-American & Caribbean Society of Medical Oncology (SLACOM) Co-Chair, Network of Latin American Cancer Institutes (RINC) .Past President - Union for International Cancer Control (UICC) , Co-Leader, The win-win initiative and Co-Director, Global Oncology-Implementing Science Courses and program, Co-founder, GO-U

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Prof. Enerique Soto Perez De Celis, MD, PhD. The Editor in Chief of ecancer, Professor of Medical Oncology & Geriatric Oncology and Associate Director for global oncology, University of Colorado , USA, He served on the Board of Directors of ASCO , he has joined the distinguished faculty of The 3^rd ASCO-GOIS International Webinar,

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Professor Karol Sikora, MA, MB BChir, PhD, MD, FRCR, FRCP, FFPM, UK , Consultant Oncologist, is the Medical Director of Cancer Partners International. He was the Founding Dean and now Professor of Medicine at Britain’s first independent Medical School at the University of Buckingham and a Fellow of Corpus Christi College, Cambridge. He was Professor and Chairman of the Department of Cancer Medicine at Imperial College School of Medicine and is still honorary Consultant Oncologist at Hammersmith Hospital, London. He was seconded to be Director of the WHO Cancer Programme in 2000. Co-Leader, The win-win initiative and Co-Director, Global Oncology-Implementing Science Courses and program, Co-founder, GO-U.

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Prof. Ahmed Elzawawy, MD, PhD, Founding Chair, win-win Scientific initiative & Co-founder & Chair, Board of Directors, GO-U & Global Oncology-Implementing Science Courses and program & Founding President, ICEDOC & Past President, AORTIC & Prof. Clinical Oncology, Suez Canal University &Chair. Clinical and Radiation Oncology Center , Port Said, Egypt.

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Prof. Hussein Khaled,

Ex. Minister of High Education , Egypt, Prof. Medical Oncology, Ex. Dean NCI , Cairo and Vice Chancellor , Cairo University , Chair , SEMCO , Co-leader, The win-win Initiative

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Prof. Wilfred Ngwa, PhD, Dana-Farber/Harvard Cancer Center, University of Massachusetts Lowell, and Johns Hopkins University, USA. He is a distinguished professor of global public health, and distinguished professor of public health. He is founding Director of the Global Health Catalyst launched at the Harvard Radcliffe Institute in 2015 He currently chairs the Africa Health and Infrastructure Committee advising the USA government on Global Health. He is a co-founder (with Prof Ahmed Elzawawy and distinguished faculty) of Global Oncology University. Founder Director, GHC& Co-founder, GO-U. Co-Leader, The win-win initiative and Co-Director, Global Oncology-Implementing Science Courses and program, GO-U

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Aparna R. Parikh, MD, FASCO, USA. Associate Professor of Medicine, Harvard Medical School , Director of the MGH Cancer Center's Global Cancer Care Program, Director of Colorectal Medical Oncology, Medical Director Center for Young Adult Colorectal Cancer, Massachusetts General Hospital Cancer Center ,Tucker Gosnell Center for Gastrointestinal Malignancies ,Termeer Center for Targeted Therapies . Dr. Parikh has a long-standing interest and background in global health and has experience in many LMICs.

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Dr Susannah Stanway, is an honorary consultant medical oncologist at the Royal Marsden Hospital in the UK, specializing in breast cancer with an interest in global cancer care. She is a past president of the Oncology Section at the Royal Society of Medicine and she is one of the founders of London Global cancer week

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Prof. Twalib A. Ngoma , Prof. Clinical Oncology , Research Chair Holder Muhimbili University of Health and Allied Sciences MUHAS , Dar es Salaam, Tanzania. Co-Leader, The win-win initiative and Co-Founder, Global Oncology University GO-U

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Bishal Gyawali, MD, PhD is an associate professor in medical oncology and public health sciences and scientist in Queen’s University, Kingston, Canada. Dr. Gyawali’ s areas of academic interests include cancer policy, evidence-based oncology, financial toxicities of cancer treatment, clinical trial methods, supportive care, cancer care disparities, and global oncology. He introduced the term “cancer groundshot” advocating for investments in implementation of proven interventions for global cancer control. He is a member of the WHO Essential Medicines List Committee for cancer drugs; ESMO-MCBS, ESMO Communications, and ESMO Public Policy committees, and ASCO-Health Equity and Outcomes Committee. He is the co-founder of the “Common Sense Oncology” movement.

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Dr. Abba Mallum is an Associate Prof of Radiation Oncology. a consultant and medical specialist at Inkosi Albert Luthuli Central Hospital in South Africa . He is actively involved in global oncology collaborations and in GOIS, GO-U.

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Dr.Jacques Bezuidenhout , Master degree of Medicine cum laude (Radboud Universiteit Nijmegen, 2009-2011) Master of Advanced Oncology (University of Ulm, 2017-2020), ESMO Academy and examination (2019), Postgraduate diploma in Health Economics (University of Cape Town, starting February 2024). His clinical work mainly urological and gastrointestinal tumors with a particular focus on MRI-guided radiotherapy.Growing up in South Africa and studying and working in different high-income countries in Europe highlighted the enormous disparities that exist in access to oncological care. This sparked his interest in global oncology.

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Upcoming webinars:

4^th& 5^th ASCO-GOIS Webinars :

- “Examples of how via scientific approaches to lower the total cost of systemic cancer therapy without compromising the outcome on patients”. They are based on virtual sessions 7- 8 &10-13 of GOIS 2023-2024 program

https://icedoc.website/GOIS_Program_2023-2024.pdf

For more information

Under preparation: Four webinars: ” How to increase access and affordability to radiation oncology and prospects of molecular radiotherapy’. ( they are based on sessions 15-21 , pages 28 -35 in the this file https://icedoc.website/GOIS_Program_2023-2024.pdf ) . It will start by May , 2025. We 'll send the Final date and time.

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If you are not register yet in GOIS , then register-for free- in www.icedoc.website , then click Register , fill the form and submit

Hence, you’ll receive the zoom links to webinars and regular information

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Acknowledgement to Mr, Doug Pyle, ASCO for collaboration with the win-win initiative since more than 2 decades & Ms, Jessica Williams and Ms. Sarah Bachmann, Global Impact , ASCO.

-We thank all the leaders and faculty of of GOIS, GO-U. and to colleagues everywhere in the world.

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ASCO- GOIS International Webinars (ASCO-GOIS IW) Series:

Be game changers in global oncology

2^nd Webinar – Notions and needs for Global Oncology-Implementing Science to increase affordability of better value global cancer care.

(Short Title: Global Oncology)

October 9, 2024 at 3.00pm-5.00pm GMT

To Register: Click www.icedoc.website then register (It is free)

ASCO: American Society of Clinical Oncology

GOIS: Global Oncology-Implementing Science Program , Global Oncology University ( GO-U)

(see https://www.icedoc.website & https://icedoc.website/GOIS_Program_2023-2024.pdf )

The ASCO- GOIS IW series are proposed, designed and facilitated by Prof. Ahmed Elzawawy, after discussions and approval of the leaders of the win-win scientific initiative and GOIS.GO-U Contact: feedback@icedoc.website & worldccoperation@gmail.com

SEMCO is The South and East Mediterranean College of Oncology

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Goals for the (ASCO - GOIS IW) Series

· Discuss the overall impact of readily available and affordable cancer therapies for patient globally in affluent and less affluent Countries (LMICs)

Specific Goals for the 2^nd session:

· Give concrete and clear notions and needs for the science of global oncology

· The needs for implementing science towards increase affordability of global better value cancer care

· Propose future directions for collaborative global cancer care studies and implementation.

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The panelists of the 2^st webinar:

· Introductory note: Prof. Robin Zon, President, ASCO 2024-2025

List of Panelists in Alphabetical order:

· Prof. Eduardo Cazap, SLACOM , RINC , ecancer , Argentina, leader , Win-win initiative & co founder GO-U & GOIS , Past President UICC, Past Chair, ASCO International Affairs Committee

· Prof Ahmed Elzawawy; Chair , Board of Directors, GO-U & Chair .The win-win Scientific Initiative, SEMCO and Past President , AORTIC & Prof. Clinical Oncology, Suez Canal University, Ismailia & ASRCO, Port Said, Egypt (The Facilitator and the contact person)

· Dr. Bishal Gyawali, MD, PhD is an associate professor in medical oncology and public health sciences and scientist in Queen’s University, Kingston, Canada. Co-founder, CSO.

Pro. David Kerr, CBE MD DSc FRCP FRCGP FACP FESMO FMedSci, Past Chair, ASCO International Affairs Committee, American Society of Clinical Oncology & Oxford University, UK , Leader , Win-Win initiative, Co-founder, GOIS, GO-U
Prof. Hussein Khaled. Prof. Medical Oncology, Ex. Minister of High Education, SEMCO & NCI, Cairo, Egypt

· Aparna R. Parikh, MD, FASCO, USA. Associate Professor of Medicine, Harvard Medical School , Director of the MGH Cancer Center's Global Cancer Care Program

Prof, Twalib Ngoma, Tanzania , board of leaders , Win-win initiative, & Co-founder, GOIS, GO-U , Past President , AORTIC
Prof. Wil Ngwa, John Hopkins University, USA, Director, GHC, GO-U, board of leaders, Win-win initiative, Co-founder GOIS

Prof. Karol Sikora, Buckingham University, UK & , leader , Win-win initiative & Co-founder, GOIS, GO-U
Rapporteur: Dr.Abba Mallum, Associate Prof Radiation Oncology and Medical cancer Consultant, South Africa and active Faculty, GOIS, GO-U.

Materials:

Ø For all colleagues : Before the webinar , it will be enjoyable to read and to watch to the materials that are considered the starting points of free panel and discussion of the upcoming webinar before 2^nd ASCO-GOIS webinar of October 9, 2024

1- PDF of slides Notions and needs for Global Oncology-Implementing Science to increase affordability of better value global cancer care.

(Short Title: Global Oncology), Introductory Overview, link: https://icedoc.website/2ndASCO-GOIS.pdf

2-Notions and needs for Global Oncology and implementing science programs. The win-win scientific initiative.

A YouTube : https://youtu.be/iRCikDtUSGM?si=UWxSatZrn2Lux2qG

3- Isn’t the time to change? (Communication in ASCO My connection)

https://icedoc.website/IsntTheTime.pdf

4- The first chapter and book summary (in the front matter) are free open access “Approaching Global Oncology. The win-win model”

https://iopscience.iop.org/book/edit/978-0-7503-3075-6

In all GOIS events and program www.icedoc.website : The objective is not to agree or not on any of the raised stimulating or brain storming points in the videos or GOIS program, but, it what is important is to arrive-freely- together to conclusive points on: What to do and future directions to increase affordability of better value cancer via scientific approaches.

====================================================================

Duration of each virtual session, 2 hours : ( RECORDED)

5 minutes: Welcome.

5 minutes: Introductory note: By Prof. Robin Zon , ASCO, President 2024-2025

20 minutes: Summary of the topic and brainstorming points.( Ahmed Elzawawy)

45 minutes: to present the raised point (s) and the summary of input of panelists, see below the tentative list ( 5 minutes for each panelist)

- Prof. Eduardo Cazap, Argentina : What is Global Oncology? The needs for Global Oncology-implementing science Educational , Training and research programs

-- Prof. Hussein Khaled, Egypt ; The increase in the gap between the required and the affordable better value affordable cancer Care .

- Prof. David Kerr UK: Optimizing Dose Selection for cancer medicines

- Prof. Karol Sikora, UK : Isn’t the time to change the game , together, as organizations or as independent in coordinated efforts, in a global win-win, smart campaign based on scientific realizable approaches? hence all stakeholders could be in a global win-win? All Stakeholders could win. New Approaches.

-Prof. Aparna Parikh, USA: The need for more scientific approaches and Implementing Science to increase the affordability of better value cancer care in the world. (We call it here: The GOAL)

- Prof. Bishal Gyawali: : Global Oncology Care. Focus on what are achievable and implementable.

. Prof. Wil Ngwa, USA: GOIS , GO-U as an example of collaborative global virtual professional cancer education focused on stimulation of more exploration of scientific approaches and Implementing Science to increase the affordability of better value cancer care in the world.

- Prof. Twalib Ngoma, Tanzania and Prof. Ahmed Elzawawy, : Project Optimus , By OCE, USA FDA) for Reforming the dose optimization and dose selection paradigm in oncology: Short note on: Why , in global cancer care in the world and in the win-win scientific initiative , we should be interested in learning its upcoming outcome? .

15 Minutes: Discussion (coordinated and facilitated)

10 minutes: Q&A

15 minutes: Conclusion and future directions

5 minutes, closing remarks

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The live discussion during the webinars and later feedback e-mails are welcomed for all. worldcooperation@gmail.com & feedback@icedoc.website

================================================

Expected Attendees:

Ø We'll send soon guides for evaluation and obtaining certificates on the program for colleagues who like to obtain certificate of different levels of “A game changer in global Oncology”. The Certificate will be after the end of each series. If you miss up to 50% of the live course for any problem of connection , wherever you are in the world , then don’t worry , all the recorded webinars will be available for all.

-------------------------------------------------------------------------------

Short information about the speakers:

President: Prof. Robin Zon, ASCO President, 2024-2025

Distinguished Scientific Experts -Panelists :

Prof. Eduardo L. Cazap MD, PhD, FASCO, Argentina , President & Founder -Latin-American & Caribbean Society of Medical Oncology (SLACOM) Co-Chair, Network of Latin American Cancer Institutes (RINC) .Past President - Union for International Cancer Control (UICC)

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Professor Karol Sikora, MA, MB BChir, PhD, MD, FRCR, FRCP, FFPM, UK , Consultant Oncologist, is the Medical Director of Cancer Partners International. He was the Founding Dean and now Professor of Medicine at Britain’s first independent Medical School at the University of Buckingham and a Fellow of Corpus Christi College, Cambridge. He was Professor and Chairman of the Department of Cancer Medicine at Imperial College School of Medicine and is still honorary Consultant Oncologist at Hammersmith Hospital, London. He was seconded to be Director of the WHO Cancer Programme in 2000. Co-Leader, The win-win initiative and Co-Director, Global Oncology-Implementing Science Courses and program, Co-founder, GO-U.

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Prof. Hussein Khaled,

Ex. Minister of High Education , Egypt, Prof. Medical Oncology, Ex. Dean NCI , Cairo and Vice Chancellor , Cairo University , Chair , SEMCO , Co-leader, The win-win Initiative

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Dr. Abba Mallum

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Upcoming webinars:

3^rd & 4^th& 5^th ASCO-GOIS Webinars :

- “Examples of how via scientific approaches to lower the total cost of systemic cancer therapy without compromising the outcome on patients. They are based on virtual sessions 7- 8 &10-13 of this program Please see pages 16 -18 &19-28 of the following Link to PDF file : GOIS program, GO-U 2023-2024 https://icedoc.website/GOIS_Program_2023-2024.pdf

Under preparation : Four webinars: ” How to increase access and affordability to radiation oncology and prospects of molecular radiotherapy’. ( they are based on sessions 15-21 , pages 28 -35 in the this file https://icedoc.website/GOIS_Program_2023-2024.pdf ) . It will start by Mid November. We 'll send the Final date and time.

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Acknowledgement Mr, Doug Pyle, ASCO for collaboration with the win-win initiative since more than 2 decades & Ms, Jessica Williams and and Ms. Sarah Bachmann, Global Impact , ASCO.

-We thank all the leaders and faculty of GOIS, GO-U.

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Don’t miss to register to GOIS program, It is free for all in the world

Click or browse www.icedoc.website then register

Hence , you’ll receive zoom link and reminders days before the webinar and more information.

Contact: Prof. Ahmed Elzawawy feedback@icedoc.website & www.icedoc.org

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GOIS-ASCO International Webinars (GOIS-ASCO IW) Series

1^st Webinar – Improving Access to Global Oncology Care through Repurposing

June 18, 2024 at 4.00pm-6.00pm GMT

ASCO: American Society of Clinical Oncology

GOIS: Global Oncology-Implementing Science Program , Global Oncology University ( GO-U)

The GOIS-ASCO International webinars ( GOIS-ASCO IW) series will continue the brainstorming reviewing and the discussion started in the Global Oncology-Implementing Science (GOIS) program virtual lectures entitled :”Be A game changer in Global Oncology”

(see https://www.icedoc.website & https://icedoc.website/GOIS_Program_2023-2024.pdf )

The GOIS-ASCO IW series are proposed, designed and facilitated by Prof. Ahmed Elzawawy, after discussions and approval of the leaders of the win-win scientific initiative and GOIS.GO-U Contact: feedback@icedoc.website & worldccoperation@gmail.com

The first webinar will cover the topic of drug repurposing in cancer care. Dr. Clare Thibodeaux, PhD, Vice President, Cures Within Reach will be moderating/coordinator this repurposing session clare@cureswithinreach.org

Session Title: Improving Access to Global Oncology Care through Repurposing (Short title: Repurposing)

Session Date / Time: June 18, 2024 at 4.00pm-6.00pm GMT

Session will be virtual and will last for 2 hours.

Goals for the (GOIS-ASCO IW) Series

· Discuss the overall impact of readily available and affordable cancer therapies for patient globally in affluent and less affluent Countries (LMICs)

Specific Goals for the 1^st session:

· Examine the opportunities and challenges of repurposed therapies to improve cancer patient care and outcomes globally, including high income countries and low and lower-middle income countries (LMICs), and how all stakeholders can work together in advancing repurposed therapies

· Propose future directions and opportunities for repurposing in global cancer care

· Attendees will enjoy more the webinar , the panels if they watch these 2 videos lecture from the GOIS course Session 14 on drug repurposing in cancer, that constitute the base of panels and further suggestions and discussions : https://www.youtube.com/watch?v=1pdYhqZSw2E&feature=youtu.be &
https://www.youtube.com/watch?v=3FIMwugnisg&feature=youtu.be

The panelists of the 1^st webinar:

The Panelists:

Pro. David Kerr, CBE MD DSc FRCP FRCGP FACP FESMO FMedSci, Chair, International Affairs Committee, American Society of Clinical Oncology & Oxford University, UK , Co-founder, GOIS, GO-U

· Prof. Eduardo Cazap, SLACOM , RINC , ecancer , Argentina, leader , Win-win initiative & co founder GO-U & GOIS , Past President UICC, Past Chair, ASCO International Affairs Committee

Dr Pan Pantziarka is the Program Director for Drug Repurposing at the Anticancer Fund and the coordinator of the Repurposing Drugs in Oncology (ReDO) project (www.redo-project.org
Prof. Karol Sikora, Buckingham University, UK & , leader , Win-win initiative & , Co-founder, GOIS, GO-U
Prof. ex. Minister of High Education, SEMCO , NCI, Cairo, Egypt

· Prof. Atara Ntekim a Clinical Oncologist with the University of Ibadan in Nigeria

· Prof Ahmed Elzawawy; The Facilitator and the contact person

Chair , Board of Directors, GO-U & Chair , The win-win Scientific Initiative & Prof. Clinical Oncology, Suez Canal University, Ismailia & ASRCO, Port Said, Egypt

· Dr. Clare Thibodeaux Ph.D : The Coordinator and The Live moderator

Vice President Cures Within Reach, USA

The starting points of free panel and discussion are based on the 2 videos:

· https://www.youtube.com/watch?v=1pdYhqZSw2E&feature=youtu.be

· https://www.youtube.com/watch?v=3FIMwugnisg&feature=youtu.be

In all GOIS events and program www.icedoc.website : the objective is not to agree or not on any of the raised stimulating or brain storming points in the videos or GOIS program, but, it what is important is to arrive-freely- together to conclusive points on: What to do and future directions.

- The discussions are open for live attendees and for sending feedback and suggestions

-The Organizers of webinars are ASCO members who will participate in the discussion and in formulation of the conclusion .

- Prof. Ahmed Elzawawy , SEMCO , ICEDOC , Chair , Board of Directors, GO-U & Chair , The win-win Scientific Initiative & Suez Canal University, Ismailia & ASRCO, Port Said, Egypt ( Facilitator & contact worldcooperation@gmail.com )

-Prof. Eduardo Cazap, SLACOM , RINC , ecancer , Argentina, leader , Win-win initiative & co founder GO-U & GOIS

- Prof. David Kerr , Oxford University , UK , , leader , Win-win initiative co- founder , GO-U & GOIS

- Prof. Karol Sikora, Buckingham University ,UK & , leader , Win-win initiative & GO-U & GOIS

- Prof. Cristina Stefan , SingHealth Duke NUS Singapore and UMF University, Main, USA& GOIS, GO-U

- Prof. Hussein Khaled , ex. Minister of High Education, SEMCO , NCI, Cairo, Egypt

- Prof Wil Ngwa, John Hopkins University , & Harvard University , USA & Director GO-U & GOIS, , leader , Win-win initiative

-Prof. Twalib Ngoma , MUHAS, Tanzania & co founder GO-U & GO-U & GOIS , , leader , Win-win initiative

Expected Attendees:

· Oncologists, pharmacists, researchers, institutions, industry members, societies and foundations and other stakeholders who are concerned with the topic, including all networks of ASCO international , ecancer, GHC, SEMCO and all partners of GOIS (https://www.icedoc.website), Unlike hundreds of classical webinars, that may haven’t lasting effects , we don’t count on the number of live attendees , but on watching the recorded sessions via many tracks and webs. Then, we consider free feedback and outcome that may last and be a stimulation for the better by many in the real world ( for feedback http://icedoc.org/feedback.html )

· The live discussion during the webinars and later feedback e-mails are welcomed for all.

· Contact for GOIS ASCO International Webinars : Please send us for any inquiry to Prof. Ahmed Elzawawy, MD, PhD

worldcooperation@gmail.com & feedback@icedoc.website

List of partners with GOIS www.icedoc.website & https://www.icedoc.website/programs.html :

ecancer.org, UK
Latin American and Caribbean Society of Medical Oncology (SLACOM)
The Network of Latin American Cancer Institutes (RINC)
The Buckingham University Medical School, UK
Bio Ventures for Global Health, USA
Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands
South Asia Centre for Medical Physics and Cancer Research
South and East College of Oncology (SEMCO)
ICEDOC.org
Muhimbili University of Health and Allied Sciences (MUHAS), Tanzania.
Cures Within Reach, USA.

N.B GOIS is formed with the contribution of faculty from renown organizations and institutions

NCI, USA; John Hopkins University, USA;
Harvard University & Dana Farber Cancer Center, USA;
Cancer Medicine Dept, University of Oxford, UK;
University of Massachusetts Lowell, USA;
University of Pennsylvania, USA;
International Cancer Experts Corps (ICEC);
American Society for Radiation Oncology (ASTRO);
Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands;
University Hospital Göteborg, Sweden;
Washington University, USA;
Georgetown University,
USA; Loyola University, USA;
University of South Florida, Tampa, USA;
National Cancer Institute Egypt;
Clinical Oncology Center, Suez Canal University, Egypt;
Alsoliman Clinical & Radiation Oncology Center, Port Said, Egypt;
Medical Oncology, University of Nairobi, Kenya;
Anhalt University of Applied Sciences, Koethen, Germany;
University of Tetova, North Macedonia;
Peace and Love Hospitals, Ghana;
College of Medicine & University College Hospital, University of Ibadan, Nigeria;
Radiation Oncology Center-Strahlentherapie, Singen/Friedrichshafen, Germany;
Clinical Oncology department, Alexandria University, Egypt;
Radiation Knowledge;
Arab Medical Association Against Cancer (AMAAC);
Plus, the list of nearly 100 contributors and affiliations in the book that compose a major base for GOIS https://iopscience.iop.org/book/edit/978-0-7503-3075-6 (List of contributors:

The live discussion during the webinars and later feedback e-mails are welcomed for all.

Contact for GOIS ASCO International Webinars: Prof. Ahmed Elzawawy, MD, PhD

worldcooperation@gmail.com & feedback@icedoc.website

The raised questions & program of session repurposing (session1 of GOIS ASCO Int. Webinars)

After reviewing these materials by the panelists and discussants:

- Repurposing and repositioning drugs and devices in cancer care

By: Prof. Ahmed Elzawawy,

https://www.youtube.com/watch?v=1pdYhqZSw2E&feature=youtu.be

& The opportunity for repurposed therapies in Low and Lower Middle Income Countries LMICs. By: Clare Thibodeaux , PhD, Vice President , Scientific Affaires , Cures Within Reach CWR, USA

https://www.youtube.com/watch?v=3FIMwugnisg&feature=youtu.be

( Optional : Chapters 23 &24 Approaching Global Oncology. The win-win model, https://iopscience.iop.org/book/978-0-7503-3075-6

Optional: The Full 14th session

https://www.youtube.com/watch?v=bkS1OEYGUkw&list=PLLUTXKBf4u_fXBLYaLLL_bBj3o3u-II-h&index=14 )

Program of 1^st webinar:

Duration of each virtual session, 2 hours : ( RECORDED)

==================================

4:00- 4:05 PM GMT -

Introduction: Ahmed Elzawawy/ David Kerr ( 5’)

==================================

4:05- 4:55

The input of panelists , Coordinator Clare Thibodeaux : ( 50’)

(5 up 8 minutes for each panelist)

( The panelist’s input may include one or more of the raised points, but he/she will contribute in the discussion of all points and in formulating the outcome and eventually in any published report or article)

The raised questions:

1-Repurposing and repositioning? ( Clare Thibodeaux) 5’

2-Why drug repurposing is important? Pan Pantziarka / David Kerr / ( total 10 minutes or 5 minutes each)

3- Barriers and obstacles? Karol Sikora / Hussein Khaled ( total 10 minutes or 5 minutes each

4- -Required actions and proposals (What to do?) Pan Pantziarka 5’ , Eduardo Cazap 5’, David Kerr 5’

5- Free Comments on the 1^st video and suggestions to include in the next season of GOIS. 10 minutes ( 5 minutes Atare Ntekim / 5 minutes Pan Pantziarka)

============================================

4:55- 5:15 PM GMT

Discussion: All 20’

========================================

5:15- 5:25 PM

Q&A 10’

=========================================

5:25-5:50

Formulation of Conclusion and future directions: All 25’

==========================================

5:50-600 PM GMT

Closing remarks: Ahmed Elzawawy / David Kerr ( 5 minutes each) 10’

==============================================

GOIS-ASCO International Webinars

Sessions Outline

Ø EACH PANELIST is COMPLETELY FREE IN PRESENTING HIS/HER SCIENTFIC INPUT AND SUGGESTION THAT COULD BE WITH OR NOT WITH THE RAISED POINTs.

THE MOST IMPORTANT IS TO ARRIVE TO CONCRETE OUTCOME AND FUTURE DIRECTIONS.

Ø A panelist could contribute in all sessions or only the session convenient to him/her.

(In case of urgent or unexpected travels with no access to internet or commitment,

then a panelist can send his free input about the raised point in a short video up to 8

minutes, to be presented in the session. Hence, we avoid cancellation of any precious

comment and input),

Ø The sessions are recorded, and will be permanently e-accessed by all in the world

and surely by the panelists. All e-feedback and more suggestions are welcomed.

This could be the subject of future panels

Ø Hence, it is hoped that these panels will be a landmark and a stimulus around

the globe for more currents of scientific works, studies and how to face

challenges of scientific implantation, focused on lowering the total costs of

cancer care without compromising the outcome and to increase affordability

of better value cancer care in the real world.

Ø All the panelists (The ASCO panelists Included) will issue a first report summarizing the outcome and future direction.

Ø The Invited panelist -after discussion with other panelists - have the right- and even. encouraged to publish reports or conferences presentations in ASCO or others or videos about any of the panel contents and outcome. Also they could add more suggestions or more updates.

Ø All follow up , reports and updated will be sent to ASCO International affairs and to all

networks.

Duration of each virtual session, 2 hours: (RECORDED)

================================

Schedule of the 1^st series of Webinars

1^st Webinar: Improving Access to Global Oncology Care through Repurposing ( Short Title: Repurposing)

2^nd Webinar: Notions and needs for Global Oncology- Implementing Science

3^rd, 4^th and 5^th Webinar: How to lower the total costs of systemic cancer treatment without compromising the outcome on patients.

==========================================

1^st Webinar: Repurposing

Stating points for free panels are the 2 videos

· https://www.youtube.com/watch?v=1pdYhqZSw2E&feature=youtu.be &
https://www.youtube.com/watch?v=3FIMwugnisg&feature=youtu.be

The Panelists are :

Facilitator:

Prof. Ahmed Elzawawy, MD, PhD

Founding Chair, win-win Scientific initiative & Co-founder & Chair, Board of Directors, GO-U & Global Oncology-Implementing Science Courses and program & Founding President, ICEDOC & Co-Chair, SEMCO & Past President, AORTIC & Prof. Clinical Oncology, Suez Canal University &Chair. Clinical and Radiation Oncology Center , Port Said, Egypt. www.icedoc.website & www.ice

Dr. Clare (Bennethum) Thibodeaux, PhD.

Vice President, Scientific Affairs at Cures Within Reach, USA

Coordinator/ Moderator

============================================

Professor David Kerr, UK

Professor David Kerr, CBE MD PhD DSc FRCP FRCGP FACP FESMO FMedSci

Chair, ASCO International affairs Committee

Professor of Cancer Medicine Oxford University, UK , where he has worked with colleagues to build a new Institute for Cancer Medicine and Cancer Hospital

Co-Leader, The win-win initiative and Co-Director, Global Oncology-Implementing Science Courses and program, Co-founder, GO-U.

==========================================

Dr Pan Pantziarka

Dr Pan Pantziarka is the Program Director for Drug Repurposing at the Anticancer Fund and was the coordinator of the Repurposing Drugs in Oncology (ReDO) project (www.redo-project.org). He is active in a broad range of activities in drug repurposing related to the scientific, medical and policy issues that are barriers to implementation. He is an active sarcoma patient advocate. In addition to repurposing, other research interests include the rare genetic cancer condition Li Fraumeni Syndrome (LFS) and the development of computational models of tumour growth. Dr Pantziarka is also the co-founder and Chairman of the George Pantziarka TP53 Trust (www.tp53.org.uk), a UK-based patient advocacy and support organisation for sufferers LFS.

Prof. Eduardo L. Cazap, Argentina

Eduardo L. Cazap MD, PhD, FASCO, Argentina , President & Founder -Latin-American & Caribbean Society of Medical Oncology (SLACOM) , Co-Chair, Network of Latin American Cancer Institutes (RINC), Past President - Union for International Cancer Control (UICC) ,Past chair, ASCO international affairs committee , Emeritus Professor-Latin American School of Oncology (ELO), Editor-in Chief – ecancer, Co editor-Global Section-The Oncologist, Ambassador, UICC Summit &Congress

Co-Leader, The win-win initiative and Co-Director, Global Oncology-Implementing Science Courses and program, Co-founder, GO-U.

===================================================================

Professor Karol Sikora,

Professor Karol Sikora, MA, MB BChir, PhD, MD, FRCR, FRCP, FFPM, UK , Consultant Oncologist, is the Medical Director of Cancer Partners International. Previously, he was the founding director of Rutherford Health, a network of cancer centres with proton beam facilities. He was the founder of Cancer Partners UK which has created UK’s largest independent UK cancer network with private equity. He was Professor and Chairman of the Department of Cancer Medicine at Imperial College School of Medicine and is still honorary Consultant Oncologist at Hammersmith Hospital, London. He was seconded to be Director of the WHO Cancer Programme in 2000.

He was the Founding Dean and now Professor of Medicine at Britain’s first independent Medical School at the University of Buckingham and a Fellow of Corpus Christi College, Cambridge. He has published over 500 papers and written or edited 20 books including Treatment of Cancer - the standard British postgraduate textbook, now going to its eighth edition in over 30 years. His new book, Cancer: the key to getting the best care - making the system work for you has created considerable controversy.

Co-Leader, The win-win initiative and Co-Director, Global Oncology-Implementing Science Courses and program, Co-founder, GO-U.

============================================================

Prof. Hussein Khaled,

Ex. Minister of High Education , Egypt, Prof. Medical Oncology, Ex. Dean NCI , Cairo and Vice Chancellor , Cairo University , Chair , SEMCO , Co-leader, The win-win Initiative

=====================================================

=================================================

Dr Atara Ntekim is a Clinical Oncologist with the University of Ibadan in Nigeria. He is a physician scientist interested in ensuring early access to effective cancer treatment by patients in sub-Sahara Africa through clinical trials. He is also working towards accelerating the implementation of precision oncology in the sub region.

====================================================

Evaluation Report.

1^st GOIS-ASCO international webinars.

===============================

With full respect and appreciation for all previous and current great and needed efforts of classical courses, in which we have the honor that most of us contributed in our ASCO and others in such efforts and most of us have leadership roles , or chairing , or organizing or as a speaker:

Please note that is not a classical educational course. But, they constructive panels , virtual webinars , to present input on brainstorming points , suggestions or even constructive critics and future directions by panelists experts on some of the approaches presented in GOIS programs to increase affordability of better value cancer care in the world.

All with the active interactions of virtual participants during and after the panels.

So, It is not the habitual short course of 2 -3 days with elementary cancer care and control education in a country then followed by rapid surveys forms that filled by audience, (even, And then to follow with reports about how this 2 days changed the practice in this country. ( Which is not easy to do and mostly not deeply really done!)

=========================================================

All the panelists (The invited ASCO panelists Included) will issue a first report summarizing the outcome and future direction.

All follow up , reports and updated will be sent to ASCO International affairs and to all networks.

Reports will include: Background, Objectives of the panels , summary , conclusions and future directions, feedback of participants and panelists , comments with annex : Agenda of the panels.

In Summary:

1^st Report after the panels

2^rdd report : it will done for the next course GOIS course and panels , October 2024 – May 2025

=============================

Questions will be announced and will be sent to all audience:

( A feedback from panelist, as well t would be appreciated)

Which of the following objectives of the course are covered in the panel :

Just reply : YES or NO ( no marks) for each objective

The objectives are that the virtual attendees, and all who will watch the recovered sessions will get these points:

1. Notions and needs for the science of Global Oncology & implementing Science. ( YES or NO)

2. Be aware of the valuable views of renown experts about many scientific approaches for the increase the affordability of better value cancer care for millions of underserved patients in the real world. ( Yes or NO)

3. To advocate to stimulate explorations of more scientific approaches that consider real conditions and to be patient centered in different communities. ( YES or NO)

4. To advocate for the needs of exploration of future directions( YES or NO)

Optional :Then

Please write 150 words max. if you would like to add comments or suggestions.

Please add clearly

1. Your name, affiliations, e-mail

2. You agree or not that your name and correspondences appear with your suggestion that will be forwarded to experts and colleagues. Also it may appear in the web www.icedoc.website and/or the next series of GOIS courses or panels

3. It is also optional if you like to send any comment or suggestion on The manuscript of the index of the first Global Oncology -implementing science GOIS Program , GO-U 2023 -2024 is issued . It is accessible to all as a link to PDF of 50 pages document Be a game changer in global oncology: https://icedoc.website/GOIS_Program_2023-2024.pdf

Contact: Please send us for any inquiry to Prof. Ahmed Elzawawy, MD, PhD

worldcooperation@gmail.com & feedback@icedoc.website

& www.icedoc.website

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